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Global Transcriptomics Technologies Market $12.7 Billion by 2027

The global market for transcriptomics technologies expected to become $12.7 billion by 2027, expanding at a CAGR of 13.6% over the forecast period, driven by wide range of applications across diverse areas of biomedical research, including different types of disease diagnosis and profiling technologies.

  • Other factors driving the market growth include increasing preference for personalized medicines by both manufactures and consumers, technological advancements and growing investment in research and development activities.
    • At the same time, continuous technological up-gradation, introduction of robust and efficient methodologies, and rising demand for more compact and reliable products are boosting the transcriptomics technologies market.
Global Transcriptomics Technologies Market

Transcriptomics technologies include techniques used to study an organism’s transcriptome, which accounts for about less than 5% of the total genome. Transcriptomics has been characterized by the development of new redefined high throughput techniques such as microarrays, gene regulation, PCR, and next generation sequencing.

  • Microarray technology allowed the assay of thousands of transcripts simultaneously at a greatly reduced cost per gene and labour saving. 
    • Advances in design and manufacture of arrays improved the specificity of probes and allowed for more genes to be tested on a single array.
      • Advances in fluorescence detection increased the sensitivity and measurement accuracy for low abundance transcripts.
  • Similarly, RNA-Seq technique allows the sequencing of transcript cDNAs, in which abundance is derived from the number of counts from each transcript.
    • The technique has therefore been heavily influenced by the development of high-throughput sequencing technologies. 
      • RNA-Seq may be used to identify genes within a genome or identify which genes are active at a particular point in time, and read counts can be used to accurately model the relative gene expression level.
    • For example, RNA-Seq can also identify disease-associated single nucleotide polymorphisms (SNP), allele-specific expression, and gene fusions, contributing to our understanding of disease causal variants. 
      • RNA-Seq of human pathogens has become an established method for quantifying gene expression changes, identifying novel virulence factors, predicting antibiotic resistance, and unveiling host-pathogen immune interactions. 
  • Over the last three decades, new technologies have integrated with other omics technologies to provide an integrated view of the complexities of cellular life. This trend is likely to continue as sequencing technologies are further developed.
Transcriptomics Technologies Market

The global transcriptomics technologies market report provides market size ($million 2017 to 2027), market share, growth trends and forecast (CAGR%, 2021 to 2027). 

The global market for transcriptomics technologies segmented by technology (gene regulation or RNA interference technology, microarrays, next generation sequencing, polymerase chain reaction), application (bioinformatics, clinical diagnostics, comparative transcriptomics, drug discovery and research), and geography.

  • Based on the technologies, the polymerase chain reaction (PCR) segment accounted for the largest share of the total market, whereas the next generation sequencing (NGS) segment expected to grow at the fastest double-digit growth rate in the coming years.
    • The PCR is highly sensitive technique which enables amplification even from very small amounts of genetic material samples.
      • The key factors influencing the growth of the PCR market are continuous product modifications, higher process efficiency, better precision and reliability of the technique, and amplification.
        • Currently, different variants of PCR such as multiplex, semiquantitative, nested, real-time and qRT-PCR are being used to enhance sensitivity and specificity of the testing methods.
    • On the other hand, the sequencing technologies are employed in the identification of novel gene sequences, detection of genetic variations, and study of functional elements of the transcriptome of various organisms.
      • Recent advances in the new generation sequencers providing high throughput screening, high speed and flexibility, and low cost led to the increased popularity of sequencing-based methods used for transcriptome analysis.
      • The transcriptome sequencing data is being used for mutational profiling, discovery and detection of non-coding RNA (nCRNA), alternative isoform discovery, gene expression profiling, and identification of aberrant transcriptional and RNA editing sites.
        • Some the commercially available NGS platforms include 454 (Roche Holding AG), Genome Analyzer (Illumina, Inc.), ABI SOLiD (Thermo Fisher Scientific/Life Technologies) and HeliScope (Helicos BioSciences).
  • In terms of applications, the clinical diagnostics segment led the global market, while the bioinformatics segment predicted to register the fastest double-digit growth rate during the forecast period.

The global market for transcriptomics technologies research report is further divided by geography into North America (U.S., Canada), Europe (U.K., Germany, France, Italy, Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of APAC), Latin America (Brazil, Mexico, Rest of LA), and Rest of the World.

  • Geographically, the North America region dominated the total market for transcriptomics technologies, followed by the Europe region, attributed to the major technological upgradation, innovation in research and development, increasing involvement of pharmaceutical and biotechnology companies and extensive applications in transcriptome analysis.
    • On the other hand, the Asia Pacific market anticipated to witness the fastest growth rate during the next few years, owing to growing focus on transcriptome research, favorable economic growth in emerging countries coupled with increasing presence of key market players and investments in the emerging markets.

The global market for transcriptomics technologies report also provides the detailed market landscape (market drivers, restraints, opportunities), market attractiveness analysis and also tracks the major competitors operating in the market and provides analysis of the company overview, financial snapshot, key products, technologies and services offered, market share analysis and recent trends in the global market.

Major competitors operating in the global market for transcriptomics technologies and included in this report are Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Danaher Corporation, Illumina, Inc., LC Sciences, LLC, Merck & Co., Inc. (MilliporeSigma/Sigma-Aldrich), Qiagen N.V., Roche Holding AG (F. Hoffmann-La Roche AG), and Thermo Fisher Scientific, Inc. (Affymetrix, Inc./Life Technologies Corp.).

  • Technology
    • Gene Regulation / RNA Interference (RNAi) Technology
    • Microarrays
    • Next Generation Sequencing (NGS)
    • Polymerase Chain Reaction (PCR)
  • Application
    • Bioinformatics
    • Clinical Diagnostics
    • Comparative Transcriptomics
    • Drug Discovery and Research
  • Geography
    • North America (U.S., Canada)
    • Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
    • Asia Pacific (Japan, China, India, Rest of APAC)
    • Latin America (Brazil, Mexico, Rest of LA)
    • Rest of the World
  • Company Profiles
    • Agilent Technologies, Inc.
    • Bio-Rad Laboratories, Inc.
    • Danaher Corporation
    • Illumina, Inc.
    • LC Sciences, LLC
    • Merck & Co., Inc. (MilliporeSigma/Sigma-Aldrich)
    • Qiagen N.V.
    • Roche Holding AG (F. Hoffmann-La Roche AG)
    • Thermo Fisher Scientific, Inc. (Affymetrix, Inc./Life Technologies Corp.)

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