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Global Intrathecal Pumps Market $368 Million by 2027

The global market for intrathecal pumps expected to reach $368 million by 2027, expanding at a CAGR of 4.7% over the forecast period, driven by advances in intrathecal drug delivery systems and its advantages in chronic pain management.

  • Technologically advanced products with improved features and large patient base affected with chronic pain and cancer are boosting the demand and rapid adoption of intrathecal pumps worldwide.
Global Intrathecal Pumps Market

Conventional drug delivery methods have shown severe drawbacks in the efficacy of treatment, due to the difficulties in administrating the optimal drug dosage to the optimal tissue site with optimal frequency. Therefore, recent efforts have been concentrating on optimizing these critical parameters by developing implantable intrathecal drug delivery devices.

  • Similarly, traditional fabrication and design methods used to limit the pump to be operated in very specific scenarios. Therefore, microfabrication utilizing integrated microelectromechanical systems has achieved fine control over the size of the devices, which has several implications when considering drug delivery including wireless monitoring of patients.
    • In particular, microdevices based on electrolytic pumps have been greatly explored in the past. These systems demonstrate the advantages of low power consumption, adequate driving force, accurate flow control and MRI compatibility.

Presently, US-FDA approved commercially available implantable intrathecal pumps include continuous infusion and programmable devices.

  • Medtronic plc, Johnson & Johnson (Codman & Shurtleff, Inc.), and Flowonix Medical, Inc. are some of the leading companies in the global intrathecal infusion pumps market, used for the treatment of pulmonary arterial hypertension, chronic intractable pain, and severe chronic pain management.
    • Combined with the use of microneedles, these integrated, miniaturized and wirelessly powered implantable drug delivery systems have a promising potential for targeted drug delivery of pain medications.

Intrathecal pump therapy is used in the treatment of severe pain conditions that have failed to respond to other modalities.

  • An intrathecal pain pump implantation, or targeted drug delivery, is used to relieve chronic pain. It is a specialized device that delivers medication directly into the cerebrospinal fluid that surrounds the spinal cord.
    • The use of intrathecal drug delivery systems (IDDSs) is most common for patients with spine disorders (post-laminectomy syndrome, compression fractures, spinal stenosis, spondylosis, and spondylolisthesis) or non-spine-related pain disorders (complex regional pain syndrome, rheumatoid arthritis, connective tissue disorders, and chronic pancreatitis). 
      • The benefits of intrathecal drug delivery includes reduction in the need for oral medications, less side effects associated with oral medications, effectiveness of therapy, outpatient procedures, less recovery time, reversible therapy, patient controlled programmer to control breakthrough pain.
    • Most commonly administrated drugs through intrathecal pumps include Baclofen, Bupivacaine, Clonidine, Hydromorphone, Midazolam, Morphine, Sufentanil, and others (ziconotide, midazoalm, fentanyl, methadone, oxycodone, tramadol, tapentadol).
    • Implanted intrathecal pumps are medical devices that are surgically implanted under the skin, typically in the abdomen. They are connected to an implanted catheter and are used to deliver prescription medicines and fluids within the body, including the intrathecal space (into the spinal fluid), to treat pain, muscle spasticity, and other diseases or conditions. Implanted pumps are periodically refilled with medicines or fluids by a health care provider.
      • They are often used to treat or manage pain after other treatments, such as oral medicines, physical therapy, or surgery, are unsuccessful.

The global intrathecal pumps market report provides market size ($million 2017 to 2027), market share, number of procedures, growth trends and forecast (CAGR%, 2021 to 2027). 

The global market for intrathecal pumps segmented by medical application by geography (pain management and spasticity management), administrated drugs [baclofen, bupivacaine, clonidine, hydromorphone, midazolam, morphine, sufentanil, and others (ziconotide, midazoalm, fentanyl, methadone, oxycodone, tramadol, tapentadol)].

  • Intrathecal infusion pumps are used in hospitals and other healthcare facilities to deliver medication for pain and spasticity in the spine in a controlled manner. These pumps have shown significant improvement in patient care by enabling controlled administration of drugs.
    • For example, Medtronic’s SynchroMed II is a programmable implanted drug-infusion system that provides drug delivery of Lioresal baclofen drug, a muscle relaxant and antispasticity agent, directly into the intrathecal space and cerebrospinal fluid from a magnetic resonance imaging-compatible pump and catheter implanted under the skin.
      • The intrathecal baclofen (ITB) therapy with the recently redesigned SynchroMed II reduces spasticity-related pain and improves quality of life more than conventional medical management with oral antispastic medications in post-stroke patients suffering spasticity.
  • In terms of revenue, the pain management application segment held the largest share of the total intrathecal infusion pumps market.

The global intrathecal pumps market research report is further divided by geography into North America (U.S., Canada), Europe (U.K., Germany, France, Italy, Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of APAC), Latin America (Brazil, Mexico, Rest of LA) and Rest of the World.

  • By geography, the North America intrathecal pumps region dominated the regional revenue share for both pain management and spasticity management segments, whereas the Asia Pacific intrathecal pumps region anticipated to witness fastest growth rates during the next few years.

The global market report also provides the detailed market landscape (market drivers, restraints, opportunities), market attractiveness analysis and profiles of major competitors in the global market including company overview, financial snapshot, key products, technologies and services offered, and recent developments.

Major competitors operating in global market for intrathecal pumps and included in the report are Debiotech S.A., Flowonix Medical, Inc., Johnson & Johnson (Codman & Shurtleff, Inc.), Medtronic plc, Tricumed Medizintechnik GmbH, and Teleflex, Inc. (Arrow International, Inc.).

  • Medical Application, by Geography
    • Pain Management, by Region (Country)
      • North America (U.S., Canada)
      • Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
      • Asia Pacific (Japan, China, India, Rest of APAC)
      • Latin America (Brazil, Mexico, Rest of LA)
      • Rest of the World
    • Spasticity Management, by Region (Country)
      • North America (U.S., Canada)
      • Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
      • Asia Pacific (Japan, China, India, Rest of APAC)
      • Latin America (Brazil, Mexico, Rest of LA)
      • Rest of the World
  • Drugs Administered
    • Baclofen
    • Bupivacaine
    • Clonidine
    • Hydromorphone
    • Midazolam
    • Morphine
    • Sufentanil
    • Others (ziconotide, midazoalm, fentanyl, methadone, oxycodone, tramadol, tapentadol)
  • Geography
    • North America (U.S., Canada)
    • Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
    • Asia Pacific (Japan, China, India, Rest of APAC)
    • Latin America (Brazil, Mexico, Rest of LA)
    • Rest of the World
  • Company Profiles
    • Debiotech S.A.
    • Flowonix Medical, Inc.
    • Johnson & Johnson (Codman & Shurtleff, Inc.)
    • Medtronic plc
    • Tricumed Medizintechnik GmbH
    • Teleflex, Inc. (Arrow International, Inc.)

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