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Global Lyophilization Equipment and Services Market $5.7 Billion by 2027

The global market for lyophilization equipment and services predicted to reach $5.7 billion by 2027, expanding at a CAGR of 3.8% over the forecast period, driven by growing biopharmaceutical industry, number of recent product approvals and increasing demand for contract manufacturing services.

Global Lyophilization Equipment and Services Market

Lyophilization or freeze drying is used to manufacture of certain pharmaceuticals and biologicals that are thermolabile or otherwise unstable in aqueous solutions for prolonged storage periods, but that are stable in the dry state. 

  • Freeze drying has been extensively used in the development of pharmaceuticals (e.g., antibiotics) and preservation of biologicals (e.g., proteins, plasma, viruses and cell lines).
    • The most common application of pharmaceutical freeze drying is in the production of injectable dosage forms, the process is also used in the production of diagnostics and, occasionally, for oral solid dosage forms where a very fast dissolution rate is desired. 
      • In the manufacturing of pharmaceutical drug products such as unstable chemicals and sterile products, the lyophilization (or freeze drying) has been widely used as an effective means. Meanwhile, lyophilization that is not optimized could take days or even weeks to terminate, which is a time- and energy-intensive process.
Lyophilization Equipment and Services Market

The global lyophilization equipment and services market report estimates the market size ($million 2017 to 2027), market share, growth trends and forecast (CAGR% 2021 to 2027).

The market for lyophilization equipment and services segmented by product (bench-top lyophilizers, rotary lyophilizers, tray lyophilizers, freeze drying microscopes), service (aseptic filling, bulk lyophilization, cycle development), application (biopharmaceuticals, diagnostics, nutraceuticals, pharmaceuticals) and geography.

  • Based on the products, the tray lyophilizers segment accounted for the largest share of the total market, attributed to increasing demand compact design, optimum performance, ease of handling, corrosion resistance and longer service life of tray-type lyophilizers.
    • The lyophilizers are used in large scale production system for variety of materials such as drug products, vaccines and injectables that allows long-term stability to avoid contamination, and breakdown of the product characteristics.
    • On the other hand, the freeze drying microscopes (FDM) segment predicted to witness the fastest growth rate throughout the forecast period, owing to closely monitoring of collapse, melting and qualitative phenomena during the lyophilization process.
      • Freeze drying microscopy provides improvements in process efficiency, with low cost and high quality of the end products, by determining the optimal freeze drying conditions of a formulation pre-lyophilization.
        • As a result, the pharmaceutical manufacturers save time and cost incurred in traditional trial-and-error approach in the lyophilization process.
  • In terms of services, the bulk lyophilization or freeze drying segment dominated the global lyophilization market, as it involves the use of industrial scale lyophilizers manufacturing products in large volumes. In addition, faster turnaround time with affordable pricing attracts more customers for outsourcing the bulk lyophilization process.
    • However, the cycle development segment estimated to register slightly higher growth rate in the near future, as it involves process development, optimization and scale-up of the lyophilization process.
      • Cycle optimization for products that are manufactured on a regular basis and on a large scale is essential. Thee freezing stage determines the degree of variations in the productivity as well as the product quality.
        • As a result, the time for lyophilization can be reduced, leading to lowering the cost of processing by experimenting with cycle development services.

The global market for lyophilization equipment and services research report is further divided by geography into North America (U.S., Canada), Europe (U.K., Germany, France, Italy, Spain, Rest of EU), Asia Pacific (Japan, China, India, Rest of APAC), Latin America (Brazil, Mexico, Rest of LA), and Rest of the World.

  • Geographically, the North America region led the lyophilization market, followed by the Europe region, due to the presence of a large number of pharmaceutical, biopharmaceutical and nutraceutical manufacturing facilities that offer lyophilization as an integral part of the manufacturing process.
    • Other factors propelling the growth in developed regions include presence of large number of standalone lyophilization facilities providing services in the healthcare industry, increasing demand for bench-top lyophilizers for R&D activities, and rapid adoption of new products and technologies.
  • However, the emerging markets anticipated to witness fastest growth rate in the next few years, due to untapped opportunities, improving healthcare infrastructure and rapidly increasing availability of low-cost and cGMP contract manufacturing and research services shifting the business trend towards the countries in Asia, Africa and Latin America regions.

The global research report also provides detailed market landscape and profiles of major companies in the global market including company overview, financial snapshot, key products, technologies and services offered, and recent developments. 

Major competitors operating in the global market for lyophilization equipment and services and included in this report are Aseptic Technologies, SA, Azbil Telstar, S.L., Baxter BioPharma Solutions (Baxter International), Biopharma Technology, Ltd., Irvine Pharmaceutical Services, Inc., LSNE Contract Manufacturing (Lyophilization Services of New England, Inc.), Lyophilization Technology, Inc., SP Scientific (SP Industries, Inc.), Thermo Fisher Scientific, Inc., W.L. Gore & Associates, Inc. and ZIRBUS Technology GmbH.

  • Product
    • Bench-top Lyophilizers
    • Rotary Lyophilizers
    • Tray Lyophilizers
    • Freeze Drying Microscope (FDM)
  • Service 
    • Aseptic Filling
    • Bulk Lyophilization (Freeze Drying)
    • Cycle Development
  • Application
    • Biopharmaceuticals
    • Diagnostics
    • Nutraceuticals
    • Pharmaceuticals
  • Geography
    • North America (U.S., Canada)
    • Europe (U.K., Germany, France, Italy, Spain, Rest of EU)
    • Asia Pacific (Japan, China, India, Rest of APAC)
    • Latin America (Brazil, Mexico, Rest of LA)
    • Rest of the World
  • Company Profiles
    • Aseptic Technologies SA
    • Azbil Telstar, S.L.
    • Baxter BioPharma Solutions (Baxter International)
    • Biopharma Technology, Ltd.
    • Irvine Pharmaceutical Services, Inc.
    • LSNE Contract Manufacturing (Lyophilization Services of New England, Inc.)
    • Lyophilization Technology, Inc.
    • SP Scientific (SP Industries, Inc.)
    • Thermo Fisher Scientific, Inc.
    • W.L. Gore & Associates, Inc.
    • ZIRBUS Technology GmbH

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